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Post by djoser-xyyman on Apr 11, 2014 12:11:23 GMT -5
Here something to make you laugh....White people are everywhere!!!
Ha! Ha! Ha! Ha! Ha! These people are insanely delusional. Really?!
Quote: The cultural implications are complex and potentially uncomfortably close to European colonial themes. "I actually am not sure there's any population that doesn't have west Eurasian [DNA]," says Reich.
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Post by anastasiaescrava on Apr 11, 2014 22:33:15 GMT -5
Looks like Herodotus/lioness/cassie gets slapped down yet again...
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Post by djoser-xyyman on Apr 14, 2014 13:09:43 GMT -5
The war continues….Hot off the press!! Logic always prevails. This is self-explanaory. Africans now have Neanderthal and Denisovan DNA….correction…it is not Neaderthal or Denisovan DNA….It is African after all.
I told you so!! In short. The so called Neanderthal/Denisovan DNA found in Eurasians are from Africans after all The truth eventually comes out.
This is a great year!!!! Warning the original study is over 60-pages. Here is the abstract. If someone needs me to break it down further…ask. Btw: Henn et al used IBD to conclude the one way migration of North Africans into lower Europe.
========== Sharing of Very Short IBD Segments between Humans, Neandertals, and Denisovans
Gundula Povysil, Sepp Hochreiter (April2014)
We analyze the sharing of very short identity by descent (IBD) segments between humans, Neandertals, and Denisovans to gain new insights into their demographic history. Short IBD segments convey information about events far back in time because the shorter IBD segments are, the older they are assumed to be. The identification of short IBD segments becomes possible through next generation sequencing (NGS), which offers high variant density and reports variants of all frequencies. However, only recently HapFABIA has been proposed as the first method for detecting very short IBD segments in NGS data. HapFABIA utilizes rare variants to identify IBD segments with a low false discovery rate. We applied HapFABIA to the 1000 Genomes Project whole genome sequencing data to identify IBD segments which are shared within and between populations. Some IBD segments are shared with the reconstructed ancestral genome of humans and other primates. These segments are tagged by rare variants, consequently some rare variants have to be very old. Other IBD segments are also old since they are shared with Neandertals or Denisovans, which explains their shorter lengths compared to segments that are not shared with these ancient genomes. The Denisova genome most prominently matched IBD segments that are shared by Asians. Many of these segments were found exclusively in Asians and they are longer than segments shared between other continental populations and the Denisova genome. Therefore, we could confirm an introgression from Deniosvans into ancestors of Asians after their migration out of Africa. While Neandertal-matching IBD segments are most often shared by Asians, Europeans share a considerably higher percentage of IBD segments with Neandertals compared to other populations, too. Again, many of these Neandertal-matching IBD segments are found exclusively in Asians, whereas Neandertal-matching IBD segments that are shared by Europeans are often found in other populations, too. Neandertal-matching IBD segments that are shared by Asians or Europeans are longer than those observed in Africans. This hints at a gene flow from Neandertals into ancestors of Asians and Europeans after they left Africa. Interestingly, many Neandertal- or Denisova-matching IBD segments are PREDOMINANTLY observed in Africans - SOME OF THEM EVEN EXCLUSIVELY. IBD segments shared between Africans and Neandertals or Denisovans are strikingly short, therefore we assume that they are very old. This may indicate that these segments stem from ancestors of humans, Neandertals, and Denisovans and have survived in Africans. ===== Am I the best or what…..lol!
The main point here is Paabo and his side-kick clowns were mis-interpreting the data all along. Or, they were just plain ole lying about NOT finding Neanderthal DNA in SSA. Neanderthal DNA found in Africans are OLDER than outside Africa. LOLOLOLOLOLOL!!!!
They games these people play.
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Post by djoser-xyyman on Apr 14, 2014 13:13:35 GMT -5
These papers are coming out faster than I can keep up!!!
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Post by djoser-xyyman on Apr 14, 2014 13:24:04 GMT -5
I am waiting on some serious research to begin on the skeletal remains on early Greeks circa 2000-500BC. So far they are staying clear of that one. I wonder why?
Arthur Evans come to mind......
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Post by djoser-xyyman on Apr 14, 2014 15:30:06 GMT -5
Sssssssoooo!!!! Paabo, Gravel and the crew were lying all along….Or they were just incompetent.
===== Quote from the recent study: 3.1.2 Sharing of IBD Segments Between Continental Populations We found that most IBD segments are observed in only one continental population, which are, in most cases, Africans. However, for non-Africans, we saw a considerable sharing of IBD segments across continental groups. The sharing between continental populations seems to CONTRADICT statements in other publications. For example, Gravel et al. (13) report that sharing of SNVs between continental groups is low.
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Post by zarahan on Apr 15, 2014 1:36:21 GMT -5
The war continues….Hot off the press!! Logic always prevails. This is self-explanaory. Africans now have Neanderthal and Denisovan DNA….correction…it is not Neaderthal or Denisovan DNA….It is African after all. I told you so!! In short. The so called Neanderthal/Denisovan DNA found in Eurasians are from Africans after all The truth eventually comes out. This is a great year!!!! Warning the original study is over 60-pages. Here is the abstract. If someone needs me to break it down further…ask. Btw: Henn et al used IBD to conclude the one way migration of North Africans into lower Europe. ========== Sharing of Very Short IBD Segments between Humans, Neandertals, and Denisovans Gundula Povysil, Sepp Hochreiter (April2014) We analyze the sharing of very short identity by descent (IBD) segments between humans, Neandertals, and Denisovans to gain new insights into their demographic history. Short IBD segments convey information about events far back in time because the shorter IBD segments are, the older they are assumed to be. The identification of short IBD segments becomes possible through next generation sequencing (NGS), which offers high variant density and reports variants of all frequencies. However, only recently HapFABIA has been proposed as the first method for detecting very short IBD segments in NGS data. HapFABIA utilizes rare variants to identify IBD segments with a low false discovery rate. We applied HapFABIA to the 1000 Genomes Project whole genome sequencing data to identify IBD segments which are shared within and between populations. Some IBD segments are shared with the reconstructed ancestral genome of humans and other primates. These segments are tagged by rare variants, consequently some rare variants have to be very old. Other IBD segments are also old since they are shared with Neandertals or Denisovans, which explains their shorter lengths compared to segments that are not shared with these ancient genomes. The Denisova genome most prominently matched IBD segments that are shared by Asians. Many of these segments were found exclusively in Asians and they are longer than segments shared between other continental populations and the Denisova genome. Therefore, we could confirm an introgression from Deniosvans into ancestors of Asians after their migration out of Africa. While Neandertal-matching IBD segments are most often shared by Asians, Europeans share a considerably higher percentage of IBD segments with Neandertals compared to other populations, too. Again, many of these Neandertal-matching IBD segments are found exclusively in Asians, whereas Neandertal-matching IBD segments that are shared by Europeans are often found in other populations, too . Neandertal-matching IBD segments that are shared by Asians or Europeans are longer than those observed in Africans. This hints at a gene flow from Neandertals into ancestors of Asians and Europeans after they left Africa. Interestingly, many Neandertal- or Denisova-matching IBD segments are PREDOMINANTLY observed in Africans - SOME OF THEM EVEN EXCLUSIVELY. IBD segments shared between Africans and Neandertals or Denisovans are strikingly short, therefore we assume that they are very old. This may indicate that these segments stem from ancestors of humans, Neandertals, and Denisovans and have survived in Africans.===== Am I the best or what…..lol! The main point here is Paabo and his side-kick clowns were mis-interpreting the data all along. Or, they were just plain ole lying about NOT finding Neanderthal DNA in SSA. Neanderthal DNA found in Africans are OLDER than outside Africa. LOLOLOLOLOLOL!!!! They games these people play. Hmm, good find. Could the older African elements NOT be NEanderthal, but evidence of a common archaic African ancestor? OR Could there have been an "African Neanderthal" type all along?
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rivertemz
Scribe
The thirst for Knowledge is strong in this one
Posts: 211
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Post by rivertemz on Apr 15, 2014 1:57:09 GMT -5
Very interesting research, I had always kept a sceptical stance on all scientific theories and findings, this has proven my patience to those studies being counteracted by new and advanced research every decade.
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Post by djoser-xyyman on Apr 15, 2014 4:54:11 GMT -5
@z-man.
That is exactly the point. the DNA is NOT Neanderthal....it is archaic homin. ie the ancestors of Neaderthal, Denisivan...AND modern humans. It is older(short IBD) in Africa because ....why? All modern humans are decendents of AFRICANS.
Some of us have vivid imagination, but that is all it is, imagination, the data tells a better story, So no, sorry, Neanderthals and AMH weren't doing the nasty.
However, don't be suprised, Paabo is not going to give up. He will attack this paper
==
oh. And as I told Lioness many times. I don't get into hypotheticals. I only discuss the data. There are millions of "what if" scenarios.
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Post by djoser-xyyman on Apr 15, 2014 4:55:57 GMT -5
Smart man! The key word you used is "patience". The truth comes out eventually. Logic prevails. Very interesting research, I had always kept a sceptical stance on all scientific theories and findings, this has proven my patience to those studies being counteracted by new and advanced research every decade.
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Post by djoser-xyyman on Apr 16, 2014 10:26:56 GMT -5
The war continues. Now they are are admitting no hybridization of Neanderthals and AMH in Iberia which was a long held belief. However they are FANATICALLY insisting on it took place in the Middle East. They are going ape trying to prove admixture but are running into a brick wall at every turn. I hope he provided proof IN the Middle East because there was no animistic sexual encounters taking place in Iberia. Lol!
========
Chronology of the earliest Upper Paleolithic in northern Iberia (Wood et al 2014)
The main conclusion -"the scene of the meeting between a Neanderthal and a Cro-magnon does not seem to have taken place on the Iberian Peninsula"- is the same as the one that has been gradually reached over the last three years by different research groups when studying key settlements in Great Britain, Italy, Germany and France. "For 25 years we had been saying that Neanderthals and early humans lived together for 8,000-10,000 years. Today, we think that in Europe there was a gap between one species and the other and, therefore, THERE WAS NO HYBRIDATION, which did in fact TAKE PLACE IN AREAS OF THE MIDDLE EAST," explained Arrizabalaga. The UPV/EHU professor is also the co-author of a piece of research published in 2012 that puts back the datings of the Neanderthals. "We did the dating again in accordance with the ultrafiltration treatment that eliminates rejuvenating contamination, remains of the Mousterian, the material culture belonging to the Neanderthals from sites in the south of the Peninsula. Very recent dates had been obtained in them -up to 29,000 years- but the new datings go back to 44,000 years older than the first dates that can be attributed to the Cro-Magnons," explained the UPV/EHU professor.
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Post by djoser-xyyman on Apr 23, 2014 7:27:48 GMT -5
Am I reading this wrong? Are they now saying that Neanderthals were BLACK? And that modern Africans(EEF) introduced light skin to Europe about 6000ya. Someone talk me off the ledge. Please! And no hypotheticals!
I need the full report.
====== Patterns of coding variation in the complete exomes of three Neandertals
Sergi Castellano et al.
We present the DNA sequence of 17,367 protein-coding genes in two Neandertals from Spain and Croatia and analyze them together with the genome sequence recently determined from a Neandertal from southern Siberia. Comparisons with present-day humans from Africa, Europe, and Asia reveal that genetic diversity among Neandertals was remarkably low, and that they carried a higher proportion of amino acid-changing (nonsynonymous) alleles inferred to alter protein structure or function than present-day humans. Thus, Neandertals across Eurasia had a smaller long-term effective population than present-day humans. We also identify amino acid substitutions in Neandertals and present-day humans that may underlie phenotypic differences between the two groups. We find that genes involved in skeletal morphology have changed more in the lineage leading to Neandertals than in the ancestral lineage common to archaic and modern humans, whereas genes involved in behavior and pigmentation have changed more on the modern human lineage.
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rivertemz
Scribe
The thirst for Knowledge is strong in this one
Posts: 211
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Post by rivertemz on Apr 23, 2014 22:53:26 GMT -5
Am I reading this wrong? Are they now saying that Neanderthals were BLACK? And that modern Africans(EEF) introduced light skin to Europe about 6000ya. Someone talk me off the ledge. Please! And no hypotheticals! I need the full report. ====== Patterns of coding variation in the complete exomes of three Neandertals Sergi Castellano et al. We present the DNA sequence of 17,367 protein-coding genes in two Neandertals from Spain and Croatia and analyze them together with the genome sequence recently determined from a Neandertal from southern Siberia. Comparisons with present-day humans from Africa, Europe, and Asia reveal that genetic diversity among Neandertals was remarkably low, and that they carried a higher proportion of amino acid-changing (nonsynonymous) alleles inferred to alter protein structure or function than present-day humans. Thus, Neandertals across Eurasia had a smaller long-term effective population than present-day humans. We also identify amino acid substitutions in Neandertals and present-day humans that may underlie phenotypic differences between the two groups. We find that genes involved in skeletal morphology have changed more in the lineage leading to Neandertals than in the ancestral lineage common to archaic and modern humans, whereas genes involved in behavior and pigmentation have changed more on the modern human lineage.
I'm so confused about how you derived that from the text in bold, pigmentation of skin can be interpreted to several biological phenotypes unrelated to Africans. And to be honest, I'm still confused by the entire research itself, I assumed if humans were able to produce a large percentage of fertile hybrids with Neanderthals, then it's most likely Neanderthals belonged to our species, but their population experienced allotropic speciation from homo sapiens for a period of time and later converged with that period's Eurasian(homo sapien) population. And it seems this research is shifting on to that assumption every time there's an scientific update to this particular field.
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Post by djoser-xyyman on Apr 24, 2014 7:48:58 GMT -5
It is always a good idea to read and try to understand before making irresponsible statements. Or, simple ask a question if you do not understand. It is irritating and nothing is learned from it. You do know that the Neandertahl admixture hypothesis assumes that ALL AMH OOA was “tapped” by Neanderthals…for the theory to work. That is why it is so ludicrous and laughable. Many of you don’t know that. That is why some scientist thinks it is so nonsensical. And I said NO hypotheticals!!! Quote by you: I assumed if humans were able to produce a large percentage of fertile hybrids with Neanderthals – ---and ---- experienced allotropic speciation from homo sapiens for a period of time and later converged with that period's Eurasian(homo sapien) population I think you are missing the point of the entire thread. There were no hybrids. Some researchers believe there was and others do NOT. The latest studies, April 2014, postulate that the so called “Neanderthal gene” indeed came from Africans. And Africans DO have the “Neanderthal gene”. Furthermore, the African version is more ancient. In case you missed it. I will clarify. The researchers have concluded that the ancestor of ALL huminins(AMH, Neanderthals and Denisovans) passed these genes on to the hominins. And no Neanderthals are NOT AMH. In addition in case you missed it. They have now concluded that AMH and Neanderthals did NOT co-exist IN Iberia, meaning they were NOT hybridizing (wink-lol!) in Iberia. And NO, the scientific update is proving the reverse – AMH were NOT banging Neanderthals…sorry. As for the text in bold on pigmentation. I am not sure what you mean by “biological phenotype unrelated to Africans”. I assume you mean white skin.? If that is the case read my “White west African thread”. Regardless, “ pigmentation changed more in modern human lineage”in the scientific sense means there is more variation in skin pigmentation genes in modern humans compared to Neandertals. This typically means more mutation ie derived ie light skin in humans. This indirectly may mean Neanderthals were dark skinned. That is why I asked for someone to talk me out of my interpretation. The Supplementals went on to talk about melanosome differences between Neanderthals and humans. They touched on Albinism. As I said before Mike is on to something but not Dravidian Albino. I will let him sort that out. I never thought about it until now, but Neanderthals being black skinned make senses. AMH in Eurasia was black up to 6000ya. This would mean the ancestor of ALL hominins were also black skinned, since “pigmentation and de-furring” took place IN the high UV latitude. The standard pigmentation genes were NOT disclosed in the Supplementals. Eg SLC45A2, SLC24A5, TYR etc but the study seem to imply that Neanderthal carried the underived/ancestral(black skin) form of pigmentation genes. To be confirmed!!!!! Quote from the study: whereas genes involved in behavior and pigmentation have changed more on the modern human lineage Am I reading this wrong? Are they now saying that Neanderthals were BLACK? And that modern Africans(EEF) introduced light skin to Europe about 6000ya. Someone talk me off the ledge. Please! And no hypotheticals! I need the full report. ====== Patterns of coding variation in the complete exomes of three Neandertals Sergi Castellano et al. We present the DNA sequence of 17,367 protein-coding genes in two Neandertals from Spain and Croatia and analyze them together with the genome sequence recently determined from a Neandertal from southern Siberia. Comparisons with present-day humans from Africa, Europe, and Asia reveal that genetic diversity among Neandertals was remarkably low, and that they carried a higher proportion of amino acid-changing (nonsynonymous) alleles inferred to alter protein structure or function than present-day humans. Thus, Neandertals across Eurasia had a smaller long-term effective population than present-day humans. We also identify amino acid substitutions in Neandertals and present-day humans that may underlie phenotypic differences between the two groups. We find that genes involved in skeletal morphology have changed more in the lineage leading to Neandertals than in the ancestral lineage common to archaic and modern humans, whereas genes involved in behavior and pigmentation have changed more on the modern human lineage.
I'm so confused about how you derived that from the text in bold, pigmentation of skin can be interpreted to several biological phenotypes unrelated to Africans. And to be honest, I'm still confused by the entire research itself, I assumed if humans were able to produce a large percentage of fertile hybrids with Neanderthals, then it's most likely Neanderthals belonged to our species, but their population experienced allotropic speciation from homo sapiens for a period of time and later converged with that period's Eurasian(homo sapien) population. And it seems this research is shifting on to that assumption every time there's an scientific update to this particular field.
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Post by djoser-xyyman on Apr 24, 2014 7:54:27 GMT -5
Hit me up if you have anymore questions.
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