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Post by djoser-xyyman on Mar 13, 2019 10:09:16 GMT -5
Ancestral mitochondrial N lineage from the Neolithic ‘green’ Sahara Vai, Stefania; Sarno, Stefania Because Africa’s climate hampers DNA preservation, knowledge of its genetic variability is mainly restricted to modern samples, even though population genetics dynamics and back-migrations from Eurasia may have modifed haplotype frequencies, masking ancient genetic scenarios. Thanks to improved methodologies, ancient genetic data for the African continent are now increasingly available, starting to fll in the gap. Here we present newly obtained mitochondrial genomes from two ~7000-yearold individuals from Takarkori rockshelter, Libya, representing the earliest and frst genetic data for the Sahara region. These individuals carry a novel mutation motif linked to the haplogroup N root. Our result demonstrates the presence of an ancestral lineage of the N haplogroup in the Holocene “Green Sahara”, associated to a Middle Pastoral (Neolithic) context. Te frst 20% of iterations were discarded as burn-in and a Maximum Clade Credibility tree was obtained using TreeAnnotator v1.8.063 and visualized with FigTree (http://tree.bio. ed.ac.uk/sofware/fgtree/). Sequence data are available for download through the National Center of Biotechnology Information as raw reads (PRJNA393833) and consensus sequences fasta fles (Accession Numbers MF479727-MF479728).
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