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Post by egyptianplanet on Jul 13, 2010 13:51:35 GMT -5
I think the reason for that is due to the diversity of Africa and the migrating of the populations at the time. They weren't stagnant quite like the Europeans and East Asians were. When sundiata's results came in telling him he was Niger-Congo a red flag came out that he's likely Yoruba: Imhotep: Africa 59% Europe 23% Asia 18% Your European ancestry, if you are from Louisiana, is probably French/German as opposed to Northern Afro-Americans that would likely be Anglo/Irish/German. The average European admixture among African-Americans in Lousinana-New Orleans is on average 21%. 79% African. Native American admixture hardly detected. I see a common trend in which pathetic samples and mislabeling in regard to Africans, leads to the appearance of decreased African ancestry... and increased European and/or Asian (Native American???) ancestry. if Imhoteps results mirros other African-Americans who tested with 23andMe his African ancestry would liekly double if tested under fair and accurate conditions. ~80%. And in regard to you, please post your results. What company are you using? 23andMe and other similar genetic companies are terriable when it comes to East Africans. If your like the Eritrean I mentioned, don't be surprised if your results read: 1% African and 99% European. Instead of the accurate ~65% African and ~35% non-African it should read, in regard to you being Lower Egyptian. I will see. I don't know which agency I'll use but I'll provide screen shots of my results. I finally stashed away enough cash to do this, being a college student money's always tight. Also in regards to 23 and me being bad to East Africans I don't know if that's what I'll use.
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Post by doctorisscientia on Jul 13, 2010 14:25:19 GMT -5
Hey guys, I found a responce by by 23andMe and their miscalculations in regard to increased Asian and/or European ancestry among African-Americans and Africans in their study.
Quote: Hello,
Thank you for writing. There is a known issue with the reported Asian/European proportion for African-Americans, which we have looked at and believe is likely to stem from the fact that African genetic diversity is very high, and the Yoruban reference dataset does not capture this diversity fully.
You are right that adding further African populations might improve Ancestry Painting, and this, among other improvements, such as the addition of Native American and South Asian reference populations, are on the table as a potential project for our Ancestry Team. We cannot say when these changes would make it to site, at this time.
As to your third question: Ancestry Painting is deterministic, so its results will be identical when run on the same genotype twice. There is some small genotyping error rate, so that the same individual run twice will have very slightly different genotypes, but such changes will almost never affect Ancestry Painting's results. The issue with African-Americans is more likely data-related than algorithm-related.
Yours,
The 23andMe Science Team
Quote: Recently researchers have made attempts to discover markers that reveal the variation in African populations, but there is still some progress to be made here. Part of the problem is the following: (3c) As has been noted in this thread, genetic diversity is higher among the indigenous peoples of Africa than it is among the indigenous people of other continents. Even when hunter-gatherer populations such as the San and Pygmies are excluded, genetic diversity is a bit higher than in other regions. How do we know this when, as I stated above, many genetic variants aren't informative for African diversity? Some studies (including the recent Tishkoff study) have looked at a set of markers called "short tandem repeats" or STRs. These markers tend to be variable in all populations, so it doesn't matter who you test when you discover them. The genotyping technology that 23andMe uses does not work for these repeat markers.
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Post by doctorisscientia on Jul 13, 2010 14:27:29 GMT -5
Also...
Quote: The estimates of % European and % Asian for African and African Americans are likely to have been strongly influenced by the use the Yoruba reference population. I agree with you that they may be overestimates. When we are able to incorporate additional African reference populations I expect to see more accurate estimates.
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Post by egyptianplanet on Jul 13, 2010 15:24:13 GMT -5
doctor- I'm thinking of opting to wait until they fix their errors and patch it up.
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Post by doctorisscientia on Jul 13, 2010 16:31:28 GMT -5
doctor- I'm thinking of opting to wait until they fix their errors and patch it up. Good decision. You don't what to end up doubting your African identity or ancestry simply because of the mistakes of a genetic company, who largely caters to Europeans.
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Post by egyptianplanet on Jul 13, 2010 19:16:22 GMT -5
tell me about it. How many "ancestry" sites translate to "trace back your European ancestors." It's getting quite tiresome. Apparently if you're a North African you're considered "Caucasian." Really? I'm Caucasian? And here I was down south being called the "n" word...
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Post by beyoku on Jul 14, 2010 8:19:01 GMT -5
Basically 23andme is taking each sample as if it is a European and seeing how much "Asian" and "African" that European sample would have. It doesent really matter if that Sample happens to be an Africa or an Asia it is treated as a European. So my profile would be: a European that is 75% African.
Ethiopian profiles come out 1 % African
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Post by anansi on Jul 14, 2010 10:22:50 GMT -5
Basically 23andme is taking each sample as if it is a European and seeing how much "Asian" and "African" that European sample would have. It doesent really matter if that Sample happens to be an Africa or an Asia it is treated as a European. So my profile would be: a European that is 75% African. Ethiopian profiles come out 1 % African Did the brother who did research on the African burial ground at the World Trade center yrs ago..for got his name was it Kittles? doesn't he have a gene mapping company? if it is indeed him why not use his company..I think they would be more incline to be more careful and conscious of what black folks are asking them to provide. I want to get my done also to see if it matches family traditions but I am not completely sold about a subject I hardly understand myself. Plucking down money without really knowing what you paid for..I donno?
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Post by doctorisscientia on Jul 14, 2010 10:42:30 GMT -5
LOL... a Kenyan on 23andME scored 50% African, 26% European, and 24% Asian. He's likely a Eastern Bantu with significant Nioltic and possibly Cushitic ancestry or vise-versa, therefore according to 23andMe 50% European and Asian.
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Post by beyoku on Jul 14, 2010 14:17:31 GMT -5
Yeah I have been speaking with him. he is of mixed Kenyan ethnicity none of which have been named.
And even when 23andMe has the opportunity to get it right they DONT:
Nope, Global Similarity is not highest with "East Africans" which uses the Kenyan Bantu sample.
-Nope he doesn't really drag toward the San in the Advanced view.
-Global Ancestry is highest with South Africans BUT he DOES NOT cluster with the "Bantu Speakers, Southern" which is the South African Bantu Sample.
-Other Aframs as well as I, Cluster closer to "Bantu Speakers, Northern" (Kenyan sample) that he does in the global view.
(The Above is what I posted in another thread)
Even when 23andme has a Kenyan they cannot properly identify him as a Kenyan. And place them with other kenyans. Sigh.
The reason I chose 23andme is they had the genetic medical information and they has a sale for 99.00 for something that would normally cost 500.00.
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Post by sundiata on Jul 18, 2010 11:16:15 GMT -5
So do you have any intentions on going to Africa to find your native tribe? I'm sure many groups contributed to my ancestry but even in terms of parental descent, the information isn't vivid enough to point to any specific group. My mtDNA has matches with the Dama in South Africa and matches in Ethiopia, but that's not saying much. According to Behar (2008), there are no known matches of my haplogroup in Mozambique so given its southern and eastern provenance, I find my maternal profile most intriguing. Maybe when I get the money, time, and information that would give me a better picture, I'd visit for that purpose. Edit: Though after browsing the raw data for my maternal lineage a bit more and comparing the information with Behar's data, I found a closer match with the Dama based on the same position of one of the defining mutations. However, I have no idea if I know what I'm reading, the only thing I'm going by is a correspondence of numbers.
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Post by kenndo on Sept 1, 2010 18:48:39 GMT -5
doctorisscientia,i send a private email to you,please check out it.
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